I don't see why not. The drivers side motor mount on the K frame is the same for either a slant six or V8 (67 - 72 pad mount). The passenger side motor mount is positioned about 1 inch farther outboard on the slant six K frame. I had hoped to use that extra room for an oil filter in the stock location on the engine but it's still too tight. A set of V8 conversion mounts should get it bolted to a V8 K frame.