Vvt lock or not
I did the 6.1 cam swap (cheap to do) on my 5.7 before I put it in my Cuda, and I also run a Mopar Performance single 4bbl intake with an Edelbrock 750 carb. I've had this setup for over 10 years now and it runs great! No fuel distribution issues that I'm aware of. I have used an Edelbrock 600 but the 750 makes more power and functions just fine on my 5.7. I am also using the MSD Hemi6 controller. I have thought about switching to a Holley Sniper TBI but the carb setup works so good I really can't justify the cost right now.