69' Dodge Dart Resto/Upgrade in NY

Will the big block headers fit with the power steering?

I also have air conditioning. Would there be enough room for that as well or would I have to give it up?

TTI says their full length headers do not fit,
https://ttiexhaust.com/TTi383440-134.htm

But their shorty headers will. Better ground clearance, too.
https://ttiexhaust.com/TTi44025.htm

You might need to go to a mini Sanden compressor for your A/C. The big old V-Twin might not clear your hood with a 440.