Quad carb setup information help

Rat, a few more questions. When you say 22 are you referring to my timing? if you are referring to timing, isnt that a lot? Ive never run anything that far advanced so will i run into cranking/starting hard when hot? And what type of machine are you referring to?
I've ordered my pin set and drill set along with a few pin vices. A question I have is once I start playing with the circuits do I do one carb at a time or do both carbs at the same time.
Anything else I need to do before starting this?
This will be a long process. I hope you are around until the end. Lol
Thanks Rod