It HAS been scientifically studied, I don't use it yet, but I will not hesitate to when My diet/exercise/supplements/aspirin stop managing My pain/arthritus/worn-out/damaged parts. I have first-hand experience with it's effectiveness, one in which the "plecebo effect" was not possible. My cousin is a PharmD, & after owning & running 3 compounding Pharmacies pushing 20yrs, working on a PhD. He has always focused on healthy habits, diet/fitness/supplementation, & natural solutions to aging/healing/quality of life. He would not use/endorse the use of anything that was not backed up by factual evidential studies.