Mopar R3 Block

Yes, the 48° has a big advantage in a all out build, valve train stability especially, and the shorter deck combinations allow a lighter reciprocating weight, at the expense of long strokes. But the OP said he was interested in a big inch street build, with victor heads, and in THAT PARTICULAR case, the the 9.6 deck, 59° combo is going to be much simpler. And cheaper.
I understand what your saying, but what's big? I think 434 cubes is pretty decent size and if he buys a water block which if I recall I am the only person that specifically mentioned that to him then even at 9.6" he will be limited by bore size. Me personally since buying a R3 block and then wanting to run Victors, both of which aren't cheap I certainly at that point wouldn't go backwards and run a 59 degree by choice.