Planning a shop build, any suggestions?

Yes, I use several types of simpson screws. Still, not as much sheer strength as a nail of equivalent size.
I use this system on the majority of my I.C.F. homes.
simpson ICF-D3.25

This is not for the truss or roof strapping. These are internal assemblies. Some external assemblies allow screws. Deck rim boards particularly. Code requires any deck to be nailed together with hangers being the main holder. I disagree, I overbuild everything.

Just had to add in that little tid bit about screws.
We use Alot of 1/2" galvanized Through Bolts w/ washers here. If it's non Accessible, Lags... I've built Alot of Docks, Porches, decks, ect... the State owns the Bay, so it best be Right!