220 is probably the biggest you want to go before you start really trade bottom end for top, mid gonna be about the same. It's a good choice for 1 hp per Cid with decent heads like mildly prepped 1.88 340/360 heads 9:1 Cr air gap headers.
Could make more with better heads LS and modern hemi's go well into the mid 400 hp with 220 ish cams.