Fuel pressure dropping while driving and under acceleration to zero at idle runs 4 lb electric Blue

Keep the Carter carb psi (In post 5) under 5. You wont need to boost reference a draw through carb on top of a supercharger. You could be seeing vaporization of fuel in the line messing with the pressure. Do you have your fuel filter vertical to the carbs? In that way the vapor wont stay in the filter but will seek its highest point, hopefully the carb bowls. I'd make sure you tank is vented too.
I have two Carter competition carburetors on top. I have a stock type sending unit that is 3/8 into the tank to the tank. Pickup filter. Line comes out down to the lower part of the frame where there is a red Holley fuel pump with a 100 micron filter and a 10 micron filter coming in and out of the Holley fuel pump going up to a fuel lab regulator and I have a 3/8 return line back to the tank.