Single or Twin turbo setup for 360?

1. A larger than optimal (what you would size for a power/response build) is what you want for towing. To stay OUT of boost in light load. The extra load (heavy truck, trailer) will make the boost when you want it.
When I said, large turbo, I’m thinking a drag race car sized.
You can go to large. Correct?
A properly size turbo would provide boost when you need it and not to early or late. This would be early by compare. Correct?
2. I suggested more cubic inches as an easier path (cheaper) to his goals. Was trying to save him some money. Not just the “internet spending his money”
No, it’s the internet spending money in which I did not agree with but choose the path of less money. Since you can throw money like the USA give rent at a problem, real or not, we’ll great for you. Does the OP?

There is no argument from me that bigger is better and a great way to go. But do so tell me the cost of a fully rebuilt engine of your thinking. Does the app have this kind of money?
3. I had a 460 ford in an F350 dually with a vortec centrifugal supercharger. It was an excellent package BECAUSE of the rising (not linear) boost curve.
Not IMO. I can see a plus to it. Though I’d rather not need to rev it up into the great boost area needed to tow something.
4. When I build an engine for ANY plan of boost, I skip right past the page where the cast and hypereutectic pistons are in the book and go straight to forged. Especially in a towing/heavy load situation. And I set them up with loose as a goose skirt clearance and huge ring gaps. Hypereutectic pistons are strong but very brittle and novice tuners will miss the tune up often and kill them. Forged will handle the long periods of heat in the crown and be more tolerant of inexperienced tuning mistakes.
That’s great! GOOD! For you. Spend that money wisely!
Does the OP intend or have the money for your fool proof plan.
Is the OP a novice at tuning?
Conservative tuning would be the start of all tuning. No doubt.
Knowing cast pistons are behind forged is a no brainer. When you wrote what you did, it seems like you have no faith in them. Break a few?