Return line fuel restriction?

I've been doing some reading and cannot seem to find a straight answer..if there is one.
Plumbing in my fuel system: from the tank I have 3/8 to 8an through 100 micron filter holley black pump 140gph through regulator then 35 micron filter to carb. On the return is where my question lies I have 8an back to the tank but the return at the tank steps all the way down to 1/4" is this restriction going to cause problems?? This will be feeding a 500" 643hp engine.
Thanks in advance for your input and help.