No issues on the 727, they were factory installed on '68s.
La/Magnum block choice will depend on what type of heads you intend to run. If you're going to run LA style heads, be aware that other than the first couple years of production, Magnum blocks were not drilled for rocker shaft oiling of LA heads. It's not a deal killer, but it will affect how you approach the rest of your build- you will need to account for the oiling by either:
Drilling the missing passage into the Magnum block.
Going to an "oil through" type lifter/pushrod/rocker system.
Supplying pressurized oil via added lines to the rocker assembly.