Depends on a lot of factors. I follow a head porter on YouTube by the name of Eric Weingartner, cool guy that just talks about head porting. Mostly Chevy stuff but he talks a little bit about mopar stuff from time to time. Anyhow he has a 12.something to 1 chebby he swears has no issues with pump swill. His truck is a pretty light S-10, big cam, plenty of converter and gears as well.
Plenty of factory cars these days with higher compression ratios. These are very finely tuned of course. Having full control of fuel and timing helps a lot.
My stroker will be about 12:1 if I stick with my current heads. It will have good quench, big cam and converter etc. But I just want a race car to drive to the coffee shop etc. If I have to run it on e85 I'll do so.