You *should* be able to run that on pump gas IF you do everything you can to help it.
Do NOT put the cam in at 104. I’ll run the numbers a bit later but I’d put it in at 107 or 108. There is zero sense shutting the intake valve 3-4 degrees early and shifting the overlap triangle.
Make sure the distributor has a curve in it. And not an “all in” by 2500 RPM. You need an actual curve.
Spark plug heat range is HUGE. You can’t just pick up a plug catalog or search the web and pick a plug. Most likely you will NOT be able to use an extended reach plug. Whatever you do, heat range is critical.
Get your coolant temp under control. That means no hotter than 160 degrees. Ever. You need as much coolant flow as you can get. You can’t get the radiator big enough.
Make sure you understand how to drive correctly. The number one issue with higher than orthodox pump gas compression ratios is loading the engine into detonation.
Any idiot can lug an engine in to detonation. That means if you are using an automatic you need to reach over and downshift if the programming isn’t perfect. And it’s usually not.
Same thing if it’s a stick. Lugging the engine below peak torque is an engine killer.
If you are going to use an OD, make sure you don’t cripple it with too high an axle ratio (numerically lower). Pay attention to your cruise RPM. Again, lugging the engine will force you into detonation.
You can make this work. You just have to think it through.