318 MAX fuel economy builds?

So my current question is... when in terms of achieving maximum fuel economy should I raise the compression ratio up to the brink of detonation? Assuming I go the route of, let's say, an RV cam, should I push it to 10:1 or so or should I drop the the compression ratio into the 8:1 or so range? I understand compression ratio when it comes to maximizing performance but I have never in my time yet made an engine for best mpg so this is exploring the land of the unknown for me. I think if I can find one I would attempt to use the Holley Economaster carb but if not I will use a TQ with the secondaries unhooked and possibly an OD trans with roughly 3.55 gears out back. Thoughts? Input?

Why not go in between? For what you are doing you have picked both extremes.

You can run 10:1 (I would) but unless you do EVERYTHING to make sure it works I’d be between 9-9.2:1 for what you want.