There is NO WAY you can build a series of engines with the same camshaft/valvetrain components in each engine to get the results that the stroke of the engine would require.
That 2" stroke engine is going to have to spin hard to make good HP. Like comparing a nascrap 358 engine that turns 8-9K and an F1 2.4L engine turning 18K while making the same peak 850 HP. One has a 3+ inch stroke the other about 1 5/8" IIRC. There is a reason that F1 cars have 7 speed gearboxes. If given the choice, F1 would run more ratios like 10. Keep the engine in the max power level at all time.