Is a 7.25 rear strong enough?

7 1/4 came stock behind 273 2bbl.

Mine has 322,000 miles on it.

It will hold up just fine
It’s good to know they will last if treated well. My 68 dart has a 360 in it and the rear end is quiet and seems fine. I drive it gently though,but I never beat on any of my cars.