Can cam support gear change?

70 Dart 340 rebuilt, compression coming in right at 9.8:1. With the lunati 703 cam. Tire height is 25.7" (245/45/17) Currently have 4.10 gears with Hemi OD 4 speed gears. Ratios are:

1st: 2.66
2nd: 1.59
3rd: 1:0
4th: .80

I'd like to have more drivability on the hwy. Was thinking about 3.23, but not sure if my cam will like that high of gear.

Thoughts?

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