I know everybody is different when it comes to pain relief. When my knee grenaded and following surgery I found that ice was the biggest help. To keep the ice from being messy, a few bags of frozen peas or similar frozen veggies were my ticket to relief. The Oxywhatever they prescribed me, I think I took about 4 of them before I got tired of them. Knee still hurt like a futhermucker after the Oxy, but I just didn't give a **** that it hurt.