You could build an engine using a 170 block, 198 crank, 225 rods and I think Neon pistons are used. This gives 205 or 210 CID, is lighter and may make more power.
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My personal opinion of doing this, is it's a waste of time and/or money. Just use a 225 motor. Easy/Peasy
Unless you are racing, and the low deck slant gives you an advantage. Slant Six racing rules allow the low deck engine to run the next lower weight class, then the same vehicle with the high deck engine.