Ford 272 C.I. runs low 11's. Why do Mopar guys need 408's?

You said hooking a bracket should be usually the least concern.

I’m asking what fast bracket cars have YOU tuned.

I didn’t think it was a hard or tricky question.
Simple. Don't build faster than you can tune. Period. If you can't hook up a 7 second full tube chassis car, then don't build one. If you need a spool, 10 inch slick and only run a 12.50, then so be it. But build what you can manage or plan on going home early. It's why I said car and driver work together.