Being a W2 user, I cant comment on the use of either head.
I would urge you to consider what parts you currently have in your stash, and use that as a deciding factor. In my case having a variety of W2 oval port stuff, like intakes, rockers, headers, etc, the Indy would be the choice for me as I have the supporting items. If you have a collection of LA intakes, headers, rockers, etc then perhaps the Eddy heads are way to go, although at those numbers I suspect they are using offset rockers and such also.
Seems to me when considering Indy, or BigMouth Eddy, we are thinking max effort deal. In truth, I could be totally wrong here, Edelbrock doesn't come to mind when I think max effort, Indy surely does.