Absolutely.
I’m running a stock bottom end with a roller regrind from Oregon Cam Grinders 214/224 on a 110 with .512 lift, 1-5/8 long tube headers and a vacuum secondary Holley 770 Street Avenger.
Using Huges 1110 springs, retainers and locks with the factory Magnum roller lifters and 1.6 rockers.
I run 95 percent of the time between 1,800 and 3k, but it’ll certainly wind up when I get on it.