I hate to say it, but that sounds like an LS. With a big or small block mopar, I would think that an aftermarket block would be first step. I dont know if the gen three bottom end is as strong as an LS.
It sounds to me that the head flow of a gen three would be the best way to get there with a mopar.
An R5P7 with a forced induction would be the easy (not cheap) way.