Paint advice needed

I'm prepping the jams and trunk on my '66 for paint and was wondering what product(s) would be adequate as a substrate for the 2K urethane single stage that I ultimately plan on shooting as a topcoat.

I'm not stripping the door jams completely but have sanded through to bare metal in spots. Can I use epoxy primer over these jams as a sealer before applying the single stage? All of the tech sheets for various epoxies that I've read seem to indicate that they can be used over "properly prepared factory finishes," but I've also read that using epoxy over enamel could be an issue. Weren't these cars covered in some type of enamel from the factory? Maybe I could rub some epoxy catalyst on a spot and see how it reacts?

Alternatively, could I just spot prime the bare spots with etch primer, then use a 2k urethane sealer, followed by the 2k urethane finish?

Short of stripping the paint completely (not gonna happen), what would you all recommend? Keep in mind this not a show car - not even close.

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