Re intake valve size, that can be overcome with boost. Given the higher pressure drop from the valves, perhaps running 15 psig boost would give similar cylinder pressure as 10 psig boost in an engine with better breathing. Bigger exhaust valves might help more since boost has no effect on their flowrate. I expect that in 10 years, there will be very affordable electric-motor blowers. There are already some you can buy which work, say $1000, though not the <$500 ones on ebay.