Edelbrock heads with OEM manifolds
To answer the original question, I ran early 340 manifolds with Edelbrock Performer RPM heads on my 65 Barracuda. The driver's side down tube did interfere with the head in the location described above (#8). Not knowing any better, I just ground on the head until the manifold fit. Never has leaked. Maybe I was just lucky. Have TTI headers now, still same heads.
To answer the original question, I ran early 340 manifolds with Edelbrock Performer RPM heads on my 65 Barracuda. The driver's side down tube did interfere with the head in the location described above (#8). Not knowing any better, I just ground on the head until the manifold fit. Never has leaked. Maybe I was just lucky. Have TTI headers now, still same heads.