NASCAR is still running pushrod motors, and Engine Masters did an 8K RPM SBC. I agree an OHC seems to make it easier, just saying that it isn't impossible to RPM a pushrod motor.
Longer stroke means higher piston speeds and slower rev's. So a longer stroke can necessitate even stronger parts and might not rev as freely.
Based on comments above, I doubt the difference between a 3.31 stroke 318/5.2 and a 3.58 stroke 360/5.9 make much difference. Just saying that stroke can play a part in the design.