Dodge 318

Depends on price and condition. AND WHAT year? Might be a Poly, is it even an LA? What year?

You at minimum will need to

Either get 6 to 8 "swap" mounts or drum up a V8 K member for your car

Likely need different exhaust manifolds

Need proper engine brackets (engine to mount brackets)--Pickup will not fit

Trans you will need to find the parts to convert to 2WD tailshaft and housing

A body front sump pan. Truck is rear sump, and will of course need oil pickup tube

Depending on year of engine and year of car you may need to change either timing cover/ water pump/ pulleys, or use radiator with appropriate lower outlet. Water pump styles and the side of exit changed about ?? 69