Rod to stroke ratio is not that critical according to the magazine tests years ago between a stock SBC 350, a 383 using the 400 rods and a 383 with the 350 rods.
According to David Vizard, a 0.5" rod change in a high compression ProStock engine makes minimal difference in power. He states low compression engines are affected more, but not a lot. This agrees with the magazine article.
Now if you are building a max petformance engine and you have the bank to support the learning curve, go for it. For most street builfs worrying over this is immaterial.