Exhaust Pros/Cons for Slant 6

I was thinking 2-1/4 since that's all the bigger my manifold outlet is
On my 2.5" SS exhaust, I used a tapered 1"? long transition right to 2.5". I opened up the CI manifold outlet as much as I felt safe, which was not a lot, and avoided as many curves as I could downstream. IMO there is a lot of restriction found by going to anything smaller than a 2.5" manifold back.