Painting defect cause?

Awesome information thank you. I sprayed the metal steering column with Eastwood Rust Encapsulator matte black, the rear seat upper metal trim with both DupliColor Caliper paint and Krylon self etching primer. Also used the caliper paint on the plastic door arm rest mounts. I think there was some sort of armor all on these as I’ve never had an issue like this and painted quite a bit. I am Planning on stripping them all and using wax/grease remover like Pre, then the self etch primer, then I may grab a different paint. I always buy lots of different brands, have yet to find a durable matte black that isn’t $25 a can like Spray Max or the Rust Encapsulator.
Thanks for that information. Using Krylon primer and Duplicolor paint might be OK, and then again it might not. There could have been a reaction. That is why I use the same brand all through any given job. If I am going to use Duplicolor paint, I will use Duplicolor primer and Duplicolor clear coat. If you want something that is real durable (like 2 part automotive paint durable) try the semi-gloss Eastwood 2K paint. It has a button on the bottom that (when pushed) releases an activator inside the can. You have about 12 hours to paint before the paint in the can hardens. It is, in essence, a 2K automotive paint. It is a bit expensive, but if you don't have spray guns and a compressor, it is a good deal.
Also, You should try to use a paint made for plastic parts when painting plastic parts. parts cannot be too clean. I go overboard cleaning parts before painting.