I don't have experience with the 750 Slayer, but I do with the 450 Slayer. Same carburetor, just smaller. I have it on the slant 6 in Vixen. I love it and it runs fantastic. The tuneability is great, with the idle and high speed air bleeds on top, idle fuel restrictors in both metering blocks and it even has bleeds under the power valve. That's some real adjustability.