Lean idle. Rich cruise.

Id be tuning to somewhere 12.5 - 13.5 at WOT

closer to 14 at cruise
looking for 14 , 14.1 14.2 if i lift off the throttle, and its running down on the idle circuits with the throttle closed on the stop. i.e higher RPM than idle, with higher vacuum and at that "raised" RPM way less chance of sucking nice oxygen up your tail pipe to mess with the reading.
The constant blow down due to the motor turning over at speed see's to that.

idle in neutral will then be what it is, and if you can get off cleanly so be it

if its making your eyes water and blackening the tail pipe, as suggested above, look to your initial advance, a bit more will clean up any just off idle problems.

The stoichiometric number for e10 is 14 to 14.1 and non ethanol fuel like 1970s leaded super or proper race stuff would be 14.7.

I have no clue about holley carbs and v8 motors with cam like yours but post above do

just don't kill yourself trying to tune to 14.7 as a baseline aim for 14 with your foot off the gas and 12.5 13 at WOT for bit of safety. do the go faster tweaking from there.

I went down a rabbit hole for a long time trying to achieve a setting that is impossible

wobbling about between 12.5 and 13.5 foot to the floor and no worse than 14.2 with it off or just a crack open

job done in my view. my plugs are not that bad Honestly :)

Dave