Low speed torque and driveability ?

To little vacuum caused by to much cam. Number one IMO. It only takes about 45 HP to move our cars down the road at 70MPH. Give or take some...
Definately correct. Automotive engines are low duty cycle designs. As you state, the power requirement is low compared to the capability. This is how OEM engines get away with small fillet radius crankshafts and narrow webs between the main and rod journals.
Aircraft engines are designed for 75% duty cycle. For takeoff they are wide open throttle and full power for 5 minutes. After that the power is reduced to 75% of maximum for the rest of the flight and possibly less for economy cruise. Running at 75% power for hours puts a lot of stress on the con rods and crankshafts, so many certified engines are required to be overhauled at 1,500 to 2,000 hours run time. Not just magnaflux rods and cranks like automotive, but x-ray to check for subsurface cracks developing. Anything that is not 100%good gets replaced. Some have put auto engines in "Experimental" or kit aircraft, but these engines generally have to be replaced at 750 to 1,000 hours as the stresses are fatigueing components.
Aircraft engines have to be light but also durable. They have wider cylinder centwr spacing to allow wider crankshaft webs and larger radius fillets for strength. Heavy duty and industrial engines are similar for strength but without the requirement to keep weight down.