Does this prove David Vizard's 128 lsa formula ?

The question was based on that to run more cr than people are generally willing to run eg 12:1 instead of 10:1 that you would have to run less than ideal timing cause of pump gas. (Wasn’t my assertion)

Say for 12:1 ideal timing was 33 degrees how much less than ideal timing would you run (for pump gas) that it becomes we’re it wasn’t worth going to 12:1, eg. 32,31,30,29,28 etc..

If I remember right that was the basic question.
Yea well that's a rabbit hole, and one argueabley worth putting effort into by a magazine or publisher interested in helping hotrodders. Certainly many of us have been on the edge of this or well into this situation (ie screw up) with both street and race setups. It's a rabbit hole because there's many approaches to the engine combination in trying to come up with the appropriate static and dynamic (another area of debate, but I think a useful tool) compression for the fuel. Yes Vizard did try to provide some guidance on this back in those books. Another work around/solution was water injection.

Also its not just the octane that effects performance. There can be two fuels of similar octane that perform differently. Not just at the track. In some of the RFG studies its been shown some engines actually run better (better mpg ) because of the oxegenates while others run worse. This stuff is above my head but I think the extreme example is if one wants to run NOx as a power booster the best results will be if the engine was designed where NOx can be favorably used.