Pertronix II users

Have taken a beak with my no run problem. To date I have checked for power at all times for ignition 1&2 , have replaced the ignition Pertronix II unit the Pertronix distributor, have the correct new coil for the Ignitor II , that Pertronix calls for. replaced spark plug wires, inc. coil wire have 8mm wires. can get engine to fire runs very very poorly, get worst and will just shut down since it is running so bad, so I do not have must time to check timing, vac . leaks, I think haveI ruled out electrical problems. Put in fresh spark plugs, cars does not run any better. I had installed a new Holley street warrior carb. p/n 0-80457s I think it is a 600 cfm unit, is long out of any warranty from them, I feel the engine running so poorly is carb. related. Is it hard to due a carb. rebuilt on something,? like there is only on be 25 miles on the carb.