Installing small cam in Stroker?

Was just thinking, since many of us are always worried about to big. Former bottom of the page guy many years ago.
We all know what to big does, I hope.
Figured it would be a good subject.
Smaller than most would go, in say a 408,416,422.Something small like 218,222 @50 high lift like Engle, Hughes, Comp, fast rate right under, over .500
10-10.5, aluimiunm heads light port to clean up/ port match. duel plane with 4bbl or six pack
2.5" exhaust on 340 manifolds cleaned up some or small headers like Dougs.
Something that would run
A/C. Pull toqure on street and have big Cubes on highway.
Or just a waste of a stroke