(2)450 DP's vs (2)750 DP's

Sounds to me like you have a lot of transfer fuel and ( [email protected]) and the transition to the mains (off the transfers) is too large of an afr gap. I’d drop the tsr and up the main jet. As a test. What’s the cruise (~2600 rpm) AFR?

Edited to add;
Looking back at your chart I see 14.9 AFR at 2900 and highest vacuum at 17in. You’re definitely on the mains there and lean, I’d step up 4 numbers on the mains and retest.
I’m really liking the increase the mains thought. What size TSR are you thinking? .065 ish? Also, by reducing the TSR won’t that cause an even leaner issue? Or will the increase in the mains increase the need for smaller TSR’s? Just trying to follow the thought process here.