Low Compression/High Boost and Pump Gas

I've built a few roots blown engines. I prefer spinning the blower. You spend a CHUNK of change on one, so use it. I don't know about any fancy formulas. I would get compression down to about a flat 7:1, maybe even 6.5 and over drive the blower. Limit total timing to no more than 34 degrees.....and back it up to see if it makes more power and it likely will all the way down to 28. Plus, now days we have all this fancy computerized boost control timing stuff like MSD so that makes it easy.