Water pump swap on 170 slant

Having problems with the water pump pulley coming in contact with the crank pulley. Is there a difference between 225 and 170 water pumps?

No, with one exception: In 1960 (only), the 170 engine used a 3-1/4" diameter impeller. All other Slant-6 water pumps have a 3-1/2" impeller. There are no differences in hub placement or other dimensions.

Please show us pics of the interference you're getting; it sounds like you might be trying to use an incorrect water pump pulley—probably not from a Slant-6; AFAIR the only differences in Slant-6 water pump pulleys are single- or double-groove; same diameter either way.