Need recommendation for a Carb for better MPG!

A pick up to a 5th avenue is apples to oranges. The Lean Burn engines were pretty efficient. Those cars also ran a low rear gear and a lock up torque converter. The pick ups of that era didn't have any of that.
Well, that's just the beginning, lets not trip over the fact that that 5th Ave. would've had the roller cam & the fast-burn chambered heads with ~9:1 squeeze....that just might matter along with the feedback carb/electronic timing controls...apples to cantelopes....