Very true with the four inch crank. I've seen that Vizard states in his seminars a positive correction factor of 0.75 for each point of compression over 10.5:1 and 0.5 of positive correction to LSA for each tenth of rocker ratio increase. So with 12.25:1 as stated by the OP, 1.3 degrees more of LSA. Anywhere from 106 to 108 should be in the sweet spot.