THREAD SIZE NEEDED

the shaft is a light interference fit at the shoulder where it goes into the control arm. the shouldered nut there is standard. the large nut at the front is somewhat interference fit. not full on stover, but definitely has some toofs to it.
So if I chase the nut and the shaft (bushing end), would a little blue loctite on the threads suffice...Or does it matter? Chasing would defeat the interference fit would it not?