Timing Mark Dilemma

Well, as others have said, the only real way to know 100% is to degree the camshaft. It's a simple process and one that I would not leave out.
Okay. I'm going with crank key pointing straight up and the #1 cylinder at TDC and leaving the marks lined up like in the second picture. On to degreeing the camshaft. Thanks again for the help....and stand by. I'm sure I'll be back!