2000 dodge caravan 14 rims with 4.5 bolt pattern

Maybe. For cheap rollers I'd give em a shot.
But, I'd bet the fronts are too tall to clear at full lock, and the rears might be too close to the fender.
I'm assuming you changed the rear pattern too. If you're using adapters, all bets are off.

(Are you dead sure the wheels are 5 on 4.5? I thought a caravan was a front driver with 5 on 100.)
I'm not dead sure. When I go look at them I would measure. Read that 14s were 5 on 4.5 and 15s were 5 on 5.