On an old school Holley 4150/60, greater than .040" of transfer slot exposure at slow idle would generally cause problems as the throttle was opened.
The sidebar Urich and Fisher's
Holley Carburetors and Manifolds covers proper throttle to transition slot relationship. (pp. 121-2 in the 1987 edition [Holley Part No. 36-73, HP Books])
The section is called
Special Procedures for Wild Camshafts
I've linked it above but the links to copyright material are often temporary.