I think if you had a lower comp street engine with a healthy cam in it, they could work very well if the engine was spec’d out properly.
Higher compression, learn from my pain!
Search some of IQ52's builds on here. Specifically what they did with a 7.35:1 440. Yeah, you read that right. He's proved time and again compression is not the end all be all. I try to preach it all the time, but get argued down so I just give up.