1971 360 question

I just picked up a 1973 Duster 340, with a 1971 360, 904 trans and 8.25 rear. I haven't checked yet, but I think the gears are 3.91's or 4.10's. The engine at some point had a fairly beefy cam installed and I'm not sure about the stall speed on the converter. My question is, the engine has an older Holley 600 cfm carb. It needs a rebuild, but I have a practically brand new Holley 4160 750 vacuum secondary laying around. Will the 750 be too much carb? Should I think about a new 650?

Second question, I have been thinking of upgrading to an MSD billet distributor with a 6AL box and coil. Is the change to a new ignition system, worth the investment?
The 4160 will be fine once tuned to your combo.
If you have the factory electronic ignition, just get the curve dialed in and you'll be fine. You'll have to do that no matter what ignition you run, and the change in ignitions (I won't say "upgrade" in this case) won't necessarily be worthwhile for your use.