Is there any way to PERMAMENTLY eliminate rear main oil leaks?

Rick Covalt said
The last 2 engines I have put together have not leaked. I spent some time removing the knurling and used the lip seal in the kits.
I would try the rope seal after two tries.

The 4 mains is a non issue. Plenty of us are running in the 275-325 HP range without issue.

Also you may or may not be surprised at how close the oil level is two the bottom of that seal when in the car. On acceleration I wouldn't be surprised that it gets covered with the oil.
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Sometimes, it's not the rear main seal. Do a positive inspection before tearing the lower end down and replacing a seal, that may not be leaking. I had a rear leak once and did a visual inspection and found a small hole, due to an aging oil pan. Drained the oil and clean off the paint at the location and applied a little JB Weld. That was 8 years ago and still a clean floor in my garage.